Repairing cartilage in osteoarthritis
نویسندگان
چکیده
منابع مشابه
Influence of acupuncture in treatment of knee osteoarthritis and cartilage repairing.
As two major non-operative methods, physiotherapy and acupuncture have been proved to be safe and effective in osteoarthritis (OA) treatment. However, only a little study focused on functions of both methods on cartilage repairing. The main goal of this research is to prove and compare effectiveness of acupuncture and physiotherapy on OA, and to explore their possible efficacy on cartilage repa...
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Osteoarthritis (OA) is one of the most common diseases among the elderly. For many years, OA was considered a normal result of the aging process with few treatment options. Remarkable progress in understanding OA cartilage has been achieved in recent years. The application of technical advances to clinical studies of chondrocytes and cartilage tissue metabolism will provide important new insigh...
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Quantitative measures of cartilage morphology (i.e., thickness) represent potentially powerful surrogate endpoints in osteoarthritis (OA). These can be used to identify risk factors of structural disease progression and can facilitate the clinical efficacy testing of structure modifying drugs in OA. This paper focuses on quantitative imaging of articular cartilage morphology in the knee, and wi...
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We studied the mechanical properties of cartilage from the apparently unaffected compartment of knees with unicompartmental osteoarthritis (OA). Plugs of cartilage and subchondral bone, 8 mm in diameter, were obtained from the tibial plateau of seven patients treated by total knee replacement. Control specimens were obtained from eight cadaver knees ofsimilar age. Specimens were loaded by a pla...
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Pan, J; Zhou, X; Scherr, T; Yang, Y; Li, B; Li, W; Yang WD; Wang, L Departments of Mechanical Engineering and Biological Sciences, University of Delaware, Newark, DE; Case Western Reserve University, Cleveland, OH; email:[email protected] Introduction Osteoarthritis (OA), a progressive disease of joint degradation, is characterized as loss of articular cartilage with associated soft and hard tiss...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2012
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd3763